Psoriatic arthritis (PsA) and systemic lupus erythematosus (SLE or lupus) are two autoimmune disorders that affect the joints and create symptoms that are comparable. There are, however, significant distinctions between the two illnesses that can assist doctors in making an accurate diagnosis and developing a suitable treatment strategy.
Skin Changes
The occurrence of cutaneous signs is one of the primary distinctions between PsA and lupus. PsA is intimately linked to psoriasis, a skin disorder characterized by scaly red areas on the skin. In fact, around 30% of patients with psoriasis will acquire PsA. Lupus is not commonly connected with skin symptoms, despite the fact that it can produce a variety of skin issues such as rashes, hair loss, and mouth ulcers.
Joint Involvement
Both PsA and lupus can affect the joints, causing pain, swelling, and stiffness. However, the patterns of joint involvement are different. In PsA, the joints are typically affected asymmetrically, which means that different joints on different sides of the body are affected. In contrast, lupus tends to cause symmetrical joint involvement, which means that the same joints on both sides of the body are affected.
Lab Tests
Both PsA and lupus can cause joint discomfort, edema, and stiffness. Yet, the patterns of collaborative engagement vary. PsA often affects the joints asymmetrically, which implies that various joints on opposite sides of the body are afflicted. Lupus, on the other hand, is characterized by symmetrical joint involvement, which implies that the same joints on both sides of the body are afflicted.
Other Symptoms
PsA and lupus can also induce a variety of additional symptoms in addition to joint and skin issues. Nevertheless, the precise symptoms of the two illnesses differ. Lupus, for example, can produce weariness, fever, and sun sensitivity, but PsA can cause ocular irritation and nail abnormalities.
Treatment
Psoriatic arthritis (PsA) is difficult to treat since it affects both the skin and the joints. PsA therapy combines medicine with non-drug treatments such as exercise, massage, heat and cold. It is tailored to your specific symptoms and illness severity.
Slow the illness and maybe put it into remission.
Relieve pain and other symptoms; and protect your skin and joints.
Any or all of the following drugs may be used to treat psoriatic arthritis:
- NSAIDs
- Biologics
- Disease-modifying antirheumatic medications (DMARDs).
- Corticosteroids
- Topical Therapies
Lupus has no cure, however therapies can help you feel better and reduce your symptoms.
Your therapy will be determined by your symptoms and requirements. The treatment aims are to:
- Avoid flares.
- Manage symptoms when they occur.
- Minimize organ damage and associated concerns.